Journal of Nature and Science of Medicine

REVIEW ARTICLE
Year
: 2020  |  Volume : 3  |  Issue : 4  |  Page : 329--333

Current understanding of probiotics and sinonasal inflammation: A review


Saud Romaih Alromaih, Nouf Mohammad Aloraini 
 Department of Otolaryngology - Head and Neck Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia

Correspondence Address:
Nouf Mohammad Aloraini
College of Medicine, King Saud University, Riyadh 13216, Saudi Arabia
Saudi Arabia

The complex interplay between commensal sinonasal microbiota and pathogenic bacteria contributes to the development of sinonasal inflammatory diseases. This review describes the rationale, effectiveness, and safety of probiotics in sinonasal inflammatory diseases. In vitro and animal clinical trials demonstrated a promising effect of probiotics in decreasing inflammation and the proportion of pathologic bacteria and improving the outcome. However, human studies involving chronic rhinosinusitis (CRS) patients did not exert any significant effect in reducing the symptoms, except in one study reported improvements in CRS exacerbations. This review concluded that up to now, the value of probiotics usage is not well understood, and future research aiming to extend the understanding of it will contribute to enhance the effectiveness of probiotic use in sinonasal inflammatory diseases.


How to cite this article:
Alromaih SR, Aloraini NM. Current understanding of probiotics and sinonasal inflammation: A review.J Nat Sci Med 2020;3:329-333


How to cite this URL:
Alromaih SR, Aloraini NM. Current understanding of probiotics and sinonasal inflammation: A review. J Nat Sci Med [serial online] 2020 [cited 2020 Nov 28 ];3:329-333
Available from: https://www.jnsmonline.org/article.asp?issn=2589-627X;year=2020;volume=3;issue=4;spage=329;epage=333;aulast=Alromaih;type=0