Journal of Nature and Science of Medicine

REVIEW ARTICLE
Year
: 2020  |  Volume : 3  |  Issue : 2  |  Page : 91--100

Allergic bronchopulmonary aspergillosis: A systematic review of its management with a call to action in Saudi Arabia


Saad Mohammed AlShareef 
 Department of Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia; Department of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria, Australia

Correspondence Address:
Saad Mohammed AlShareef
Department of Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh; Department of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Victoria

Allergic bronchopulmonary aspergillosis (ABPA) is a relatively common, but underdiagnosed allergic complication of asthma and cystic fibrosis, occurring in about 13% and 9% of cases, respectively. Significant progress has been made over the last decade in establishing diagnostic criteria and a pragmatic clinical approach to its management with steroids, antifungals, and newer agents, including anti-immunoglobulin E (IgE) monoclonal antibodies. In spite of this, there is very little literature on ABPA in Saudi Arabia, and the few papers that do exist suggest that ABPA may be associated with Aspergillus species other than Aspergillus fumigatus. This is of particular concern since the recommended current diagnostic screening is based on A. fumigatus-specific IgE levels, and other Aspergillus species may have different clinical profiles. This article provides an overview of ABPA for the practicing physician, provides an up-to-date review of randomized controlled trials in ABPA, and highlights urgent research priorities for ABPA in Saudi Arabia.


How to cite this article:
AlShareef SM. Allergic bronchopulmonary aspergillosis: A systematic review of its management with a call to action in Saudi Arabia.J Nat Sci Med 2020;3:91-100


How to cite this URL:
AlShareef SM. Allergic bronchopulmonary aspergillosis: A systematic review of its management with a call to action in Saudi Arabia. J Nat Sci Med [serial online] 2020 [cited 2020 Oct 22 ];3:91-100
Available from: https://www.jnsmonline.org/article.asp?issn=2589-627X;year=2020;volume=3;issue=2;spage=91;epage=100;aulast=AlShareef;type=0